2005-2007
Platforms and networks in triterpenoid pharmacology. Drug Develop Res 68:174-182, 2007. https://onlinelibrary.wiley.com/doi/abs/10.1002/ddr.20179
Triterpenoids and rexinoids as multifunctional agents for prevention and treatment of cancer. Nat Rev Cancer 7:357-369, 2007. https://www.nature.com/articles/nrc2129
The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta. Mol Cancer Ther 5:3232-3239, 2006.
https://pubmed.ncbi.nlm.nih.gov/17148759/The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells. Clin Cancer Res, 12:4288-4293, 2006. https://clincancerres.aacrjournals.org/content/12/14/4288.long
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Res 65:4789-4798, 2005. https://cancerres.aacrjournals.org/content/65/11/4789